ABSTRACT
Plasmacytosis is a condition in which there are an unusually large proportion of plasma cells in tissues, exudates, or blood. Reactive plasmacytosis is a diagnosis of exclusion, to be differentiated from other autoimmune, allergic and neoplastic disorders with plasma cell infiltrates. This paper describes a rare case of 73-year-old male patient diagnosed as plasmocytosis depending upon the clinical and histological findings. There was chronic inflammatory enlargement of the gingiva and palate with severe periodontitis. Histopathological examination revealed a stratified squamous orthokeratinized epithelium with underlying fibrocellular connective tissue stroma. The connective tissue showed intense infiltrate of small round cells of plasmacytoid type with eccentrically placed nucleus suugestive of reactive plasmacytosis.The diagnostic and management challenges encountered are described in this case report.
ABSTRACT
Corticosteroids (Cs) are used widely for their anti-inflammatory and immunosuppressive properties. However their long-term administration may lead to impaired periodontal health. The aim of the present study was to clinically assess the periodontal status in patients on long-term corticosteroid therapy. Periodontal health of 100 patients under long-term corticosteroid therapy for a minimum of 6 months duration was compared with sex- and age-matched 100 healthy controls. The periodontal examination included measuring oral hygiene index-simplified (OHI-S), gingival index (GI), sulcus bleeding index (SBI), probing pocket depth (PPD) and clinical attachment loss (CAL). The results showed that mean values of OHI-S, GI and SBI did not differ significantly (p>0.05) between cases and controls. Mean PPD and CAL was significantly higher in cases when compared to the controls (p = 0.0003). Within the limitations of the study, it can be concluded that there is a positive correlation between periodontal status and long term steroid therapy.